ورزش و علوم زیست حرکتی

ورزش و علوم زیست حرکتی

تغییرات مقادیر سرمی اینترلوکین 15 و نیمرخ لیپیدی، متعاقب مداخله تمرین هوازی با شدت متوسط در مردان میان‌سال مبتلا به سندروم متابولیک

نوع مقاله : مقاله پژوهشی

نویسندگان
1 دانشجوی کارشناسی ارشد فیزیولوژی ورزشی، گروه علوم ورزشی، دانشکده علوم تربیتی و روانشناسی، دانشگاه شهید مدنی آذربایجان، تبریز، ایران
2 دانشیار فیزیولوژی ورزشی، گروه علوم ورزشی، دانشکده علوم تربیتی و روانشناسی، دانشگاه شهید مدنی آذربایجان، تبریز، ایران
3 دکتری فیزیولوژی ورزشی، گروه علوم ورزشی، دانشکده علوم تربیتی و روانشناسی، دانشگاه محقق اردبیلی، اردبیل، ایران
چکیده
مقدمه و هدف: تقویت جذب گلوکز در بدن توسط اینترلوکین 15 و اختلالات متابولیکی مرتبط با آن در بیماران مبتلا به سندروم متابولیک احتمالا با مداخله فعالیت ورزشی هوازی دستخوش تغییراتی گردد. هدف این مطالعه بررسی تاثیر یک دوره تمرین هوازی بر سطوح IL-15 و شاخص ­های خطر متابولیک می ­باشد.
مواد و روش ­­ها: تعداد 20 مرد مبتلا به سندروم متابولیک بصورت داوطلبانه انتخاب و بطور تصادفی در دو گروه 10 نفری کنترل و تمرین قرار گرفتند. برنامه تمرین شامل 12 هفته تمرین هوازی با  3 جلسه در هفته و هرجلسه شامل 45 دقیقه­ تمرین با شدت 70-60 درصد ضربان قلب اوج بود. خون­گیری در مراحل قبل و بعد از مداخله تمرین جهت اندازه ­گیری متغیرهای خونی شامل IL-15، HDL، LDL، تری­گلیسرید، کلسترول­تام و گلوکز خون انجام شد. داده­ ها بوسیله آزمون های آماری تی وابسته و مستقل در سطح معنی ­داری 0.05 تحلیل شد.
یافته­ ها: در همه متغیرها بین دو گروه تفاوت معناداری وجود داشت. در گروه تمرین مقادیر IL-15، HDL، حداکثر اکسیژن بیشینه در پس­ آزمون نسبت به پیش ­آزمون افزایش معنادار داشت (0.05>P). در وزن بدن،  شاخص توده بودنی، دور کمر، فشار خون میانگین، کلسترول­ تام، تری­گلیسرید، LDL، قند خون و شاخص مقاومت به انسولین کاهش معنادار مشاهده شد (0.05>P).
بحث و نتیجه ­گیری: 12 هفته برنامه تمرین هوازی با شدت متوسط را می ­توان برای کنترل عوامل خطر متابولیک در بیماران دارای سندروم متابولیک بعنوان یک روش غیرداروئی پیشنهاد نمود.
کلیدواژه‌ها

عنوان مقاله English

Changes in serum levels of interleukin 15 and lipid profile following the intervention of moderate intensity aerobic exercise in middle-aged men with metabolic syndrome

نویسندگان English

Kobra Rasi 1
Bahloul Ghorbanian 2
Asgar Iranpour 3
1 MSc student of Exercise Physiology, Department of Sport Sciences, Faculty of Educational Sciences and Psychology, Azerbaijan Shahid Madani University, Tabriz, Iran
2 Associate Professor of Exercise Physiology, Department of Sport Sciences, Faculty of Educational Sciences and Psychology, Azerbaijan Shahid Madani University, Tabriz, Iran
3 Ph.D. of Exercise Physiology, Department of Sport Sciences, Faculty of Educational Sciences and Psychology, Mohaghegh Ardabili University, Ardabil, Iran
چکیده English

Introduction and purpose: Glucose absorption improves in the human body by IL-15 and related metabolic disorders in patients with metabolic syndrome (MS) may be affected by aerobic exercise. The aim of this study was to investigate the effect of an aerobic exercise session on interleukin-15 levels and metabolic risk factors.
Materials and methods: In this study 20 men with MS were selected voluntarily and randomly divided into two control (n=10) and aerobic exercise (n=10) groups. The exercise program included 12weeks of aerobic exercise with 3 sessions per week and each session consisted of 45 minutes of exercise with an intensity of 60-70% of the maximal heart rate. Blood samples were taken from the subjects before and after the intervention of the exercise program to measure blood variables including IL-15, HDL, LDL, TG, TC, and blood glucose. The data were analyzed by independent and dependent sample t-tests at a significance level of 0.05.
Results: There is a significant difference between the two groups in all variables. In the exercise group, in the post-test compared to the pre-test, the values of IL-15, HDL, and VO2peak significantly increased (P<0.05).  The values of BW, BMI, WC, MBP, TC, TG, LDL, FBS, and insulin resistance index had a significant decrease (P<0.05).
Discussion and conclusion: 12 weeks of moderate- intensity aerobic exercise program can be suggested as a non-drug method to control metabolic risk factors in patients with metabolic syndrome.

کلیدواژه‌ها English

Aerobic exercise
Interleukin-15
Metabolic syndrome
Lipid profile
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دوره 14، شماره 28 - شماره پیاپی 28
پاییز و زمستان
اسفند 1401
صفحه 96-104

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