ورزش و علوم زیست حرکتی

ورزش و علوم زیست حرکتی

تاثیر دوازه هفته تمرین ترکیبی (هوازی و پیلاتس) بر سطوح سرمی بیومارکرهای آنتی اکسیدانی در زنان مبتلا به سرطان پستان

نوع مقاله : مقاله پژوهشی

نویسندگان
بهلول قربانیان 1
یوسف صابری 2
الناز حمیدی 3
1 دانشیار، گروه علوم‌ورزشی، دانشکده علوم‌تربیتی و روانشناسی، دانشگاه شهیدمدنی آذربایجان، تبریز، ایران.
2 دکترای،‌‌‌ گروه علوم ورزشی، دانشکده علوم تربیتی و روانشناسی، دانشگاه شهید مدنی آذربایجان، تبریز، ایران.
3 کارشناس‌ارشد، گروه علوم‌ورزشی، دانشکده علوم‌تربیتی و روانشناسی، دانشگاه شهیدمدنی آذربایجان، تبریز، ایران.
10.22034/sbs.2024.445065.1084
چکیده
مقدمه و هدف: بررسی ها نشان می ­دهد بین سطوح آنتی ­اکسیدان­ های درون زاد و خطر ابتلا به سرطان پستان و بازرخداد آن ارتباط وجود دارد. فعالیت ورزشی به عنوان یک راهکار موثر در پیشگیری و درمان سرطان شناخته شده است. از طرفی نقش فعالیت ­های ورزشی ترکیبی بویژه ورزش پیلاتس و هوازی بر این عوامل در بیماران سرطانی مشخص نیست. هدف مطالعه حاضر بررسی تغییرات برخی آنتی ­اکسیدان­ های درونزاد زنان یائسه مبتلا به سرطان پستان متعاقب ۱۲ هفته فعالیت ورزشی ترکیبی بود.
مواد و روش­ ها: در این مطالعه نیمه تجربی ۳۰ زن مبتلا به سرطان پستان تحت درمان به عنوان آزمودنی­ های در دسترس انتخاب و بطور تصادفی به دو گروه تجربی و کنترل تقسیم شدند. گروه تجربی به مدت ۱۲ هفته و هر هفته ۳ جلسه به فعالیت ورزشی پیلاتس و هوازی پرداختند و گروه کنترل در این مدت در هیچ برنامه فعالیت ورزشی شرکت نکردند. قبل و بعد از مداخله تمرین نمونه خونی جهت سنجش متغیرهای مورد مطالعه اخذ شد. داده­ ها با استفاده از آزمون تی مستقل و وابسته در سطح معناداری کوچکتر از 0.05 تحلیل شدند.
یافته ­ها: نتایج نشان داد پس از ۱۲ هفته تمرین ترکیبی، سطوح گلوتاتیون پراکسیداز (0.005=P) و ظرفیت آنتی‌اکسیدانی تام در گروه تجربی در مقایسه با گروه کنترل افزایش معنی­ داری داشتند (0.05>P)، اما تغییرات سطوح سوپراکسید دیسموتاز و مالون­دی آلدئید معنی دار نبود (0.05<P).
نتیجه­ گیری: به نظر می ­رسد تمرین ترکیبی هوازی و پیلاتس می ­تواند اثرات سودمندی برای دفاع آنتی ­اکسیدانی آنزیمی از طریق افزایش گلوتاتیون پراکسیداز، سوپراکسید دیسموتاز و ظرفیت آنتی ­اکسیدانی تام در زنان مبتلا به سرطان پستان داشته باشد که شاید پیامد آن کاهش بازرخداد یا متاستاز سرطان پستان باشد.




 
کلیدواژه‌ها
تمرین ترکیبی
سرطان پستان
سوپراکسید دیسموتاز
گلوتاتیون پراکسیداز
مالون­دی آلدئید
ظرفیت آنتی‌اکسیدانی تام

موضوعات

عنوان مقاله English

The effect of weekly combined exercise (aerobics and pilates) on the serum level of antioxidant biomarkers in women with breast cancer

نویسندگان English

Bahloul Ghorbanian 1
yousef saberi 2
elnaz hamidi 3
1 Associate Professor, Department of Sport Sciences, Faculty of Psychology and Education, Azarbaijan Shahid Madani University, Tabriz, Iran.
2 Ph.D, Department of Sport Sciences, Faculty of Psychology and Education, Azarbaijan Shahid Madani University, Tabriz, Iran
3 M.Sc, Department of Sport Sciences, Faculty of Psychology and Education, Azarbaijan Shahid Madani University, Tabriz, Iran.
چکیده English

Introduction and Purpose: Studies show that there is a relationship between the levels of endogenous antioxidants and the risk of breast cancer and its recurrence. Sports activity is recognized as an effective way to prevent and treat cancer. On the other hand, the role of combined sports activities, especially Pilates and aerobics, in influencing these factors in cancer patients is not clear. The aim of the present study was to investigate changes in certain endogenous antioxidants in postmenopausal women with breast cancer after 12 weeks of combined sports activity.
Materials and Methods: In this semi-experimental study, 30 women with breast cancer undergoing treatment were randomly selected as available subjects and divided into two groups: experimental and control. The experimental group participated in Pilates and aerobics for 12 weeks, with three sessions per week, while the control group did not engage in any sports program during this period. Before and after the training intervention, blood samples were taken to assess the studied variables. The data were analyzed using independent and dependent t-tests at a significance level of less than 0.05.
Results: The results showed that after 12 weeks of combined training, the levels of glutathione peroxidase (P=0.005) and total antioxidant capacity in the experimental group significantly increased compared to the control group (P<0.05). However, changes in the levels of superoxide dismutase and malondialdehyde were not significant (P>0.05).
Conclusion: It appears that combined aerobic and Pilates training can have beneficial effects on enzymatic antioxidant defense by increasing GPX, SOD, and TAC levels in women with breast cancer, which may help reduce the recurrence or metastasis of breast cancer

کلیدواژه‌ها English

Combined exercise
Breast cancer
Superoxide dismutase
Glutathione peroxidase
Malondialdehyde
Total antioxidant capacity
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ورزش و علوم زیست حرکتی
دوره 16، شماره 32
اسفند 1403
صفحه 15-27

  • تاریخ دریافت 02 اسفند 1402
  • تاریخ بازنگری 28 مهر 1403
  • تاریخ پذیرش 08 آبان 1403