Introduction: The aim of the present study was to investigate the responses of plasma visfatin to resistance exercise volume and its relationship with insulin resistance index, IL-6 and growth hormone.
Methods: Fifteen healthy young subjects (age: 23.9±1, weight: 74.4±7.2, BMI: 26.1±3.6) were volunteered to participate in the study. After familiarization and determining the maximum strength (1-RM), subjects performed two resistance exercise protocols of 3-sets and 5 sets randomly at two separate occasions with one week intervening. Three blood samples were taken before exercise, immediately after exercise and after 30 min recovery, and were analyzed for growth hormone, interlukin-6 (IL-6) and visfatin. Insulin resistance index was calculated using glucose and insulin concentrations. To compare the responses of parameters to exercise and recovery, the differences between pre and post exercise as well as pre and post recovery data were calculated and compared by using paired t-test.
Results: Results showed that there were no significant differences between the responses of these parameters to two resistance exercise volumes (P>0.05). Irrespective of resistance exercise volume, single session of resistance exercise resulted in significant (P < 0.001) changes in all variables except for visfatin. Investigating the statistical correlations of data in response to exercise showed no significant relationship among all variables with visfatin.
Conclusions: The results of this study show that resistance exercise volume is not an affective factor on plasma concentration of visfatin and that visfatin cannot be considered as one of the affective factors in insulin resistance process.
Key words: Resistance exercise volume, maximum strength, visfatin, interlukin-6