Journal of Sports and Biomotor Sciences

Journal of Sports and Biomotor Sciences

Comparison of the effect of combined exercises (resistance-aerobic) with ginger and cinnamon supplements on some glycemic indices in obese postmenopausal women with type 2 diabetes

Authors
Abstract
Introduction and purpose: Diabetes is an inflammatory disease caused by long-term imbalance of the immune system, metabolic syndrome and excess energy associated with obesity. In addition to its role in the prevention of diabetes, exercise also helps in the treatment of diabetes and significantly improves insulin sensitivity and diabetes-related health disorders with minimal side effects.
Materials and methods: In this research, which was semi-experimental with a pre-test-post-test design, 23 obese women with diabetes were selected as an available sample and trained randomly in two groups using a one-way blind design. Combined exercise and cinnamon consumption (12 people, height 154.17±4.69, weight 75.45±6.62, body mass index 31.7±1.7) and combined exercise and ginger consumption (11 people, height 154.45±4.03, weight 75.18±6.09, body mass index 1.56± 31.46) were placed. The people who were in the ginger consumption group received 1500 mg of ginger rhizome powder daily for eight weeks, and the people who were in the cinnamon consumption group received cinnamon capsules according to the same plan. Both groups performed resistance training and aerobic interval training (running) with an intensity of 75-85% of maximum heart rate for eight weeks, three sessions per week. The indicators were measured 48 hours before the first training session and after eight weeks of training to determine changes in glucose, insulin and insulin resistance index. Analysis of variance with repeated measurements was used to check the mean difference of the desired variables. A significance level of α ≤ 0.05 was considered.
Results: No significant difference was observed between the changes in the glucose in the studied groups (P>0.05), but a significant decrease was observed in the insulin and insulin resistance in the group of combined exercises and cinnamon compared to the group of combined exercises and ginger. (P = 0.0001).
Discussion and Conclusion: According to the results of this research, it seems that resistance-aerobic exercises and cinnamon consumption show better efficiency for improving glycemic indices.
Keywords

1. Verma S, Hussain ME. Obesity and diabetes: an update. Diabetes Metab Syndr. 2017;11(1):73-79. 2. Xia C, Rao X, Zhong J. Role of T lymphocytes in type 2 diabetes and diabetes-associated inflammation. J Diabetes Res. 2017;:6494795. 3. Olokoba AB, Obateru OA, Olokoba LB. Type 2 diabetes mellitus: a review of current trends. Oman Med J. 2012;27(4):269-73. 4. Gheibi N, Parvizi M, Jahani Hashemi H. The effect of cinnamon on glucose concentration of diabetic rats in presence or absence of insulin. J Quazvin uni Med Sci 2005; 9(3):3-8. 5. Begzadeh, Mehdi, Hosseinpour, Siddiqa, Safikhani, Hassan. The effect of aerobic exercise with cinnamon consumption on insulin resistance index and plasma levels of blood glucose, visfatin and adiponectin in overweight men with type 2 diabetes. Journal of Applied Sports Physiology, (2017). 14(28), 173-178. 6. Khan, A. Bryden, N. A. Polansky, M. M. & Anderson, R. A. Insulin potentiating factor and chromium content of selected foods and spices.Biological trace element research,1990 ; 24(2-3): 183-188. 7. Azimi, P. Ghiasvand, R. Feizi, A. Hosseinzadeh, J. Bahreynian, M. Hariri, M. & Khosravi-Boroujeni, H. Effect of cinnamon, cardamom, saffron and Ginger consumption on blood pressure and a marker of endothelial function in patients with type 2 diabetes mellitus: A randomized controlled clinical trial. Blood pressure, 2016 ; 25(3): 133-140. 8. Soleimani Z, PIRI M. Comparision the effect of high intensity interval training and continuous endurance training on expression of MYOD in soleus muscle of diabetic rats. journal of sport and exercise physiology. 2016;2:1213-21 . 9. Jeon YK, Kim SS, Kim JH, Kim HJ, Kim HJ, Park JJ, et al. Combined Aerobic and Resistance Exercise Training Reduces Circulating Apolipoprotein J Levels and Improves Insulin Resistance in Postmenopausal Diabetic Women. Diabetes Metab J. 2020;44(1):103-112. 10. American Diabetes Association. Gestational diabetes mellitus. Diabetes Care, 2004 ;‌27(1):‌88-90.15.. 11. Egger, A. Niederseer, D. Diem, G. Finkenzeller, T. Ledl-Kurkowski, E. Forstner, R. Different types of resistance training in type 2 diabetes mellitus: effects on glycaemic control, muscle mass and strength. European journal of preventive cardiology,2012 ; 20(6): 1051-1060 12. Gholaman Masoumeh, Gholami Mandana, Azarbayjani Mohammad Ali, Abed Natanzi Hossein. High and Moderate Intensity Aerobic Training Effects on Galectin-3, Pentraxin-3, and Several Inflammatory Mediators Levels in Type 2 Diabetic Women, a Randomized Clinical Trial. Journal of Women’s Health Bulletin . 2021 , Volume 8 , Number 4; Page(s) 238 To 246. 13. Rashidlamir A, Alizadeh A, Ebrahimiatri A, Dastani M. The Effect of Four-Week Period of Aerobic Exercise with Cinnamon Consumption on Lipoprotein Indicates and Blood sugar in Diabetic Female Patients (Type 2). 2013; 20 (5) :605-614. 14. Mohamadi B, Sheikholeslami-vatani D,The effect of 8 weeks of resistance training with cinnamon consumption on glucose, blood pressure, insulin resistance and glycosylated hemoglobin in postmenopausal women with type 2 diabetes, (Master Thesis). University of Kurdistan.2016.. 15. Askari R, Haghighi A H, Badri N. Comparison Of The Effects Of Combined Training With And Withoutzingeber Supplement On Lipid Peroxidation And Antioxidant Capacity In Type 2 Diabetic Women. ijdld. 2018; 17 (4) :165-172 . 16. Esmaelzadeh Toloee M.R, Faramarzi M, Noroozian P. Effect of Aerobic Training with Ginger Supplementation on some Liver Enzymes (AST,ALT,GGT) and Resistance to Insulin in Obese Women with Type 2 Diabetes, 2017 ; 60 (4): 636-647. 17. Ismail AD, Aba Alkhayl FF, Wilson J, Johnston L, Gill JMR, Gray SR. The effect of short duration resistance training on insulin sensitivity and muscle adaptations in overweight men. Exp Physiol. 2019; 104(4):540-545 18. Asadi M, Banitalebi E, Esfadir Z, Ghafari M. The Effect of A Period Rhythmic Aerobic Exercise With Ginger Consumption On Serum Levels Of TNF-Α, IL-6 And Insulin Resistance In Obese Middle-Aged Women With Diabetes Mellitus. Armaghane danesh. 2017; 22 (1):32-47 19. Blevins, S. M. Leyva, M. J. Brown, J. Wright, J. Scofield, R. H. & Aston, C. E. Effect of cinnamon on glucose and lipid levels in Non–insulin-dependent type 2 diabetes. Diabetes care. 2007 ;30(9), 2236-2237. 20. Howard, M. E. & White, N. D. Potential benefits of cinnamon in type 2 diabetes. American Journal of Lifestyle Medicine. 2013 ; 7(1): 23-26. 21. Pourmasoumi, M. Hadi, A. Rafie, N. Najafgholizadeh, A. Mohammadi, H. & Rouhani, M. H. (2018). The effect of Ginger supplementation on lipid profile: A systematic review and meta-analysis of clinical trials. Phytomedicine. 2018 . 1;43:28-36. 22. Fatouros, I. G. Chatzinikolaou, A. Tournis, S. Nikolaidis, M. G. Jamurtas, A. Z. Douroudos, I. I. & Mitrakou, A. Intensity of resistance exercise determines adipokine and resting energy expenditure responses in overweight elderly individuals. Diabetes care. 2009; 32(12): 2161-2167. 23. Hoehn, K. L. Salmon, A. B. Hohnen-Behrens, C. Turner, N. Hoy, A. J. Maghzal, G. J. & Richardson, A. R. Insulin resistance is a cellular antioxidant defense mechanism. Proceedings of the National Academy of Sciences. 2009; 106(42): 17787-17792. 24. Li, Y. Tran, V. H. Duke, C. C. & Roufogalis, B. D. Gingerols of Zingiber officinale enhance glucose uptake by increasing cell surface GLUT4 in cultured L6 myotubes. Planta medica. 2012; 78(14), 1549-1555. 25. Khan, A. Safdar, M. Khan, M. M. A. Khattak, K. N. & Anderson, R. A. Cinnamon improves glucose and lipids of people with type 2 diabetes. Diabetes care. 2003; 26(12): 3215-3218. 26. Atashak S, Peeri M, Jafari A, Azarbayijani M. Effects of 10 week resistance training and ginger consumption on c-reactive protein and some cardiovascular risk factors in obese men. Physiol Pharmacol. 2010;14(3):318- 28. 27. Vanschoonbeek, K. Thomassen, B. J. Senden, J. M. Wodzig, W. K. & van Loon, L. J. Cinnamon supplementation does not improve glycemic control in postmenopausal type 2 diabetes patients. The Journal of nutrition. 2006; 136(4) 977-980. 28. Mahluji, S. Attari, V. E. Mobasseri, M. Payahoo, L. Ostadrahimi, A. & Golzari, S. E. Effects of ginger (Zingiber officinale) on plasma glucose level, HbA1c and insulin sensitivity in type 2 diabetic patients. International journal of food sciences and nutrition. 2013; 64(6): 682-686. 29. Wang Y, Simar D, Fiatarone MA. Adaptations to exercise training within skeletal muscle in adults with type 2 diabetes or impaired glucose tolerance: a systematic review. Diabetes Metab Res Rev. 2009; 25(1): 13-40. 30. Lee, K. J. Shin, Y. A. Lee, K. Y. Jun, T. W. & Song, W. Aerobic exercise training-induced decrease in plasma visfatin and insulin resistance in obese female adolescents. International journal of sport nutrition and exercise metabolism. 2010; 20(4): 275-281. 31. Park, S. W. Goodpaster, B. H. Strotmeyer, E. S. De Rekeneire, N. Harris, T. B. Schwartz, A. V. & Newman, A. B. Decreased muscle strength and quality in older adults with type 2 diabetes: the health, aging, and body composition study. Diabetes. 2006; 55(6): 1813-1818. 32. Colberg, S. R. Sigal, R. J. Fernhall, B. Regensteiner, J. G. Blissmer, B. J. Rubin, R. R. & Braun, B. Exercise and type 2 diabetes: the American College of Sports Medicine and the American Diabetes Association: joint position statement. Diabetes care. 2010; 33(12):147-167. 33. Andersen, H. Nielsen, S. Mogensen, C. E. & Jakobsen, J. (2004). Muscle strength in type 2 diabetes. Diabetes. 2004; 53(6): 1543-1548. 34. Li, Y. Tran, V. H. Duke, C. C. & Roufogalis, B. D. (2012). Gingerols of Zingiber officinale enhance glucose uptake by increasing cell surface GLUT4 in cultured L6 myotubes. Planta medica, 78(14), 1549-1555.

  • Receive Date 23 November 2022
  • Revise Date 27 February 2023